Beilstein J. Org. Chem.2022,18, 660–668, doi:10.3762/bjoc.18.67
with good operational stability, evaluated by a constant high yield of cyclohexene oxide, to obtain the desired product with high productivity.
Keywords: air; continuous flow; cyclohexene oxide; flow epoxidation; rapidgas–liquidreaction; Introduction
From the past to the present, organic synthesis
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Graphical Abstract
Scheme 1:
Synthesis of cyclochexene oxide via epoxidation with air in the presence of isobutyraldehyde.